Metabolic microdosing · BMI 20+You don't have to be in crisis to invest in your metabolism.

Yes. The Metabolic Microdosing program has a BMI eligibility floor of 20. A licensed provider will still review your full health history before prescribing, but BMI over 20 is sufficient to begin the intake process. If your BMI is below 20, contact our care team to discuss options.

It's built around different goals, not just a smaller dose. The formulas are specifically compounded for metabolic optimization, energy, sleep, blood sugar regulation, and maintenance — not emergency weight reduction. The clinical protocols, consult rhythms, and coaching modules are distinct from full GLP-1 programs. That said, the active pharmaceutical ingredients (semaglutide, tirzepatide) are the same compounds used in full programs, just at lower concentrations matched to a precision-wellness objective.

At lower doses, typical GI side effects (nausea, fatigue, reduced appetite) are usually milder for most patients. Your care coach covers side effect management in your first session, and your provider can adjust your dose at any regular check-in.

Take the free 90-second quiz — it routes you to the most appropriate formula based on your goals, health context, and BMI. Your licensed provider will confirm or adjust the recommendation during your consultation. If your needs change during treatment, formula transitions happen at your next provider check-in.

Yes, and it's designed to be seamless. If your goals shift, your BMI changes, or your provider recommends escalating to a full GLP-1 program, the transition happens within the same platform — same provider network, same member portal, same care coach. There are no re-enrollment fees. Your new plan starts at the next billing cycle.

Injection formulas (Sema Inject, Tirz Inject) are subcutaneous self-injections administered once weekly. They require cold-chain shipping and refrigerated storage. Oral tablet formulas (ODT = oral disintegrating tablet) dissolve under the tongue — no needles, no refrigeration, room-temperature storage. Both deliver the same active pharmaceutical compounds. Your preference is a valid clinical consideration, and your provider factors it into their recommendation.

Compounded GLP-1 microdosing contains actual pharmaceutical compounds (semaglutide, tirzepatide) that require a licensed provider's prescription — these are not supplements. Every patient is individually reviewed by a licensed provider before any medication ships.

Microdosing is an off-label use pattern — it isn't part of an FDA-approved dosing schedule for semaglutide or tirzepatide at any strength; it's a lower-dose protocol your provider prescribes based on clinical judgment, not a use case the FDA has separately reviewed. GLP-1 medications have an established safety profile at standard, FDA-approved doses, studied over several years of clinical use. Long-term data specifically on low-dose, maintenance-style use is less extensive, simply because this pattern of use is newer — most large studies were designed around full-dose, time-limited treatment. That's why microdosing patients still have regular provider check-ins and lab review for as long as they're on a formula, the same monitoring cadence used for full-dose programs. Your provider reassesses whether continuing, adjusting, or stopping makes sense at each check-in.

Coverage for microdosing varies by insurance plan and is not guaranteed. Like all Bold You programs, microdosing is offered on a direct-pay basis — we recommend checking with your insurance provider about your specific coverage before enrolling.

People who are pregnant, breastfeeding or planning a pregnancy, or who have a personal or family history of medullary thyroid cancer or MEN 2, a history of pancreatitis, type 1 diabetes, or an eating disorder. Your provider reviews your full history.

Many people notice changes in appetite within the first few weeks. Body composition and energy changes build more gradually.