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Hormone Replacement Therapy — Coming Soon

Your Hormones Changed.
Your Care Should Keep Up.

Clinician-prescribed hormone replacement therapy for perimenopause, menopause, and hormone imbalance — personalized to your biology. Multiple formulations. All 50 states. Launching soon.

Learn How It Works →
[Photo: Confident woman, late 40s, warm natural smile, bright modern living room, afternoon natural light]
From $66/mo
Multiple formulations
All 50
States
Quarterly
Provider review
Discreet
Delivery
Licensed Physicians in All 50 States
Multiple Formulation Options
Quarterly Provider Review
FSA/HSA Accepted
Cancel Anytime
You Are Not Imagining It

You Are Not Imagining It

Hot flashes. Poor sleep. Mood changes. Brain fog. Weight that does not respond the way it used to. Joint pain. Reduced libido. These are not inevitable parts of aging and they are not in your head. They are the documented measurable effects of declining estrogen and progesterone — hormones that affect virtually every system in your body including your brain, cardiovascular system, bones, metabolism, and urogenital health.

For decades women were undertreated or dismissed when raising these concerns. The medical conversation has shifted significantly. Modern clinician-prescribed hormone therapy is recognized as an effective evidence-supported option for women experiencing these symptoms — particularly when initiated within 10 years of menopause onset or before age 60.

You deserve a provider who listens and takes action. Our licensed independent clinicians specialize in women’s hormone health.
Hot flashes or night sweats disrupting sleep or daily life
Sleep disruption — difficulty falling asleep, staying asleep, or waking unrested
Mood changes, irritability, or anxiety that feel unlike your baseline
Brain fog or difficulty with focus and memory
Weight gain that does not respond to diet and exercise the way it used to
Vaginal dryness or discomfort affecting quality of life
Reduced libido or changes in sexual response
Joint pain or stiffness
Changes in menstrual cycle patterns — perimenopause
Fatigue that sleep does not resolve
[Photo: Woman, late 40s, natural expression, bright airy home environment, warm natural light]
The Science, Made Simple

How Estrogen and Progesterone Work — And Why Their Decline Matters

Estradiol — the primary form of estrogen — acts on receptors throughout the body. In the brain it supports mood, cognition, sleep, and temperature regulation. In the cardiovascular system it supports arterial flexibility and lipid metabolism. In the skeletal system it maintains bone density. In the metabolic system it supports insulin sensitivity and fat distribution. In the urogenital system it supports vaginal health and bladder function. When estradiol declines during perimenopause and menopause every system it supports feels the change. Progesterone works alongside estrogen — balancing its effects on the uterine lining and contributing independently to sleep quality and mood regulation.

Modern HRT uses 17-beta estradiol — molecularly identical to the estrogen your ovaries produced — rather than the synthetic conjugated estrogens used in older formulations. The safety concerns from an influential 2002 study were largely specific to the synthetic formulation studied, not to modern bioidentical estradiol. Updated clinical guidance from major medical organizations reflects this distinction.

Think of HRT as restoring what your body lost — not adding something foreign. For women experiencing significant symptoms the conversation has shifted from whether HRT is safe to whether its benefits outweigh the risks for your individual situation. That is exactly the conversation your BoldYou provider is trained to have with you.

What to Expect and When

Week 1–4Hormone levels begin adjusting. Some patients notice sleep improvements first. Hot flash frequency may begin decreasing.
Week 4–8Most patients report meaningful improvement in hot flashes, mood stability, and sleep quality.
Week 8–12Vaginal health improvements become more noticeable. Energy and libido begin returning.
Month 3 and beyondFull effects on mood, cognition, body composition response, and overall wellbeing. Quarterly provider review confirms levels and adjusts formulation if needed.
Formulation Options

Your Formulation Options — Clinician Recommended Based on Your Profile

HRT is not one-size-fits-all. The right formulation depends on your symptoms, health history, personal preferences, and whether you have had a hysterectomy. Your provider reviews all of these before recommending. All options are billed quarterly — every 12 weeks.

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Estradiol Pill + Progesterone

$66 /month ($199 every 12 weeks)
Oral estradiol with oral progesterone

Daily oral tablet. Most straightforward routine. Progesterone included for women with intact uterus to protect the uterine lining.

Best for: Patients who prefer the simplicity of daily oral medication and have no liver concerns.

[Photo: Patch on forearm, clean clinical minimal photography]

Estradiol Patch or Cream + Progesterone

$89 /month ($269 every 12 weeks)
Transdermal estradiol with oral progesterone

Patch worn on skin changed per schedule, or cream applied daily. Bypasses first-pass liver metabolism entirely.

Best for: Patients with liver concerns or certain cardiovascular risk factors for whom transdermal delivery is preferred. Also patients who prefer not to take a daily oral tablet.

[Photo: Gel applicator, clean minimal photography]

Estradiol Vaginal Gel or Insert + Progesterone

$83 /month ($249 every 12 weeks)
Local vaginal estradiol with progesterone as indicated

Applied vaginally. Lower systemic absorption than systemic formulations.

Best for: Women with primarily urogenital symptoms — vaginal dryness, discomfort, recurrent UTIs, or bladder changes — who want targeted local treatment with minimal systemic effects.

[Photo: Tablet on clean surface, minimal photography]

Non-Hormonal Options

$59 /month ($178 every 12 weeks)
Paroxetine 10mg or Desvenlafaxine 50/100mg

Daily oral tablet.

Best for: Women who cannot take hormone therapy — history of hormone-sensitive cancers, certain clotting disorders, or personal preference for non-hormonal treatment. Paroxetine is FDA-approved for vasomotor symptom reduction. Desvenlafaxine has clinical evidence for hot flash reduction.

Your provider determines the appropriate formulation, dose, and whether progesterone is indicated based on your individual health history and whether you have had a hysterectomy. Women who have had a hysterectomy may not require progesterone.

Full Transparency

Lab Testing for HRT — What to Expect

Unlike our GLP-1 and TRT programs, HRT does not require mandatory baseline labs in all cases. Your provider orders labs based on your symptom profile and health history. If labs are ordered they are billed directly to you — they are not included in HRT pricing.

Labs That May Be Ordered Depending on Your Situation
FSH (Follicle-Stimulating Hormone)Helps confirm menopause stage and ovarian function.
EstradiolBaseline hormone level to guide formulation and dosing.
Thyroid PanelThyroid conditions can closely mimic menopause symptoms — important to rule out.
ProgesteroneBaseline level.
Comprehensive Metabolic PanelLiver and kidney health baseline.
Lipid PanelCardiovascular health baseline.
Your provider may determine labs are not necessary based on your symptom presentation alone. This is an individual clinical decision. Labs that are ordered are billed directly to you at Quest or Labcorp — not included in your HRT monthly price.
Eligibility

Who Qualifies — and Who Should Discuss Carefully

Good Candidates

Women experiencing symptoms of perimenopause or menopause
Women in postmenopause seeking ongoing hormone support
Women with hormone-related symptoms at any stage — perimenopause, menopause, or postmenopause
No contraindications identified during provider review
Located anywhere in the 50 states

Have an Honest Conversation With Your Provider If You Have

History of hormone-sensitive breast or uterine cancer
History of blood clots — deep vein thrombosis or pulmonary embolism
Active liver disease
Uncontrolled high blood pressure
Current pregnancy or breastfeeding

This is not a complete list. Many women with complex histories are still candidates for some form of hormone support — including non-hormonal options. The conversation with your provider is what matters. Accurate disclosure during intake is essential.

Full Transparency

Side Effects — What to Expect

We believe in complete transparency. Here is what the research shows and how your provider monitors for each.

Common and Manageable
Breast tendernessCommon in early weeks as hormone levels adjust. Usually resolves as levels stabilize.
Spotting or irregular bleedingPossible in the first 3–6 months with combined HRT. Report persistent or heavy bleeding to your provider promptly.
Mood changesSome patients experience fluctuations during the adjustment period. Typically resolves within 8–12 weeks.
NauseaMore common with oral estradiol. Transdermal options often reduce or eliminate this.
HeadacheSome patients report headaches during dose adjustment periods.
Important Considerations to Discuss With Your Provider
Breast cancer riskDepends significantly on formulation, dose, duration, and individual factors. Modern low-dose bioidentical estradiol has a different risk profile than older synthetic formulations. Your provider discusses your personal risk profile directly.
Blood clot riskOral estrogen has a small increased risk. Transdermal estradiol appears to have a neutral risk profile — one reason it is often preferred for women with certain cardiovascular risk factors.

These are clinical discussions your provider has with you directly based on your complete health history. Side effects and risks vary significantly between individuals and formulations.

Pricing

HRT Pricing — Everything Included

All HRT programs are billed quarterly — every 12 weeks. One price covers your clinician-prescribed medication, quarterly provider review, and ongoing oversight.

FormulationMonthlyEvery 12 Weeks
Estradiol pill + progesterone$66/mo$199
Estradiol patch or cream + progesterone$89/mo$269
Estradiol vaginal gel + progesterone$83/mo$249
Non-hormonal option$59/mo$178
Labs: Ordered as clinically needed — billed directly to you at Quest or Labcorp. Not included in HRT pricing unlike our GLP-1 and TRT programs.
Care coaching: Not included in HRT. Optional video therapy consults available at $149/session for patients who want deeper support.
Nothing else. No membership fees. No platform fees.
Stacks Well With

Programs That Work Well With HRT

Many patients combine HRT with other programs to address multiple aspects of their health simultaneously. Your provider guides what makes clinical sense for your individual situation.

Available Now

HRT + GLP-1 Microdosing

Weight gain during perimenopause and menopause is hormonal — not a willpower issue. HRT addresses the hormonal environment. GLP-1 microdosing addresses the appetite and metabolic changes that drive the weight gain. Together they address both sides of the problem simultaneously.

from $235/month
Learn about GLP-1 Microdosing →
Available Now

HRT + NAD+

Hormonal changes and cellular aging often compound each other. HRT addresses hormonal decline. NAD+ supports the cellular energy systems that affect how you feel daily — energy, mental clarity, and the biological processes underlying healthy aging. Many women report that NAD+ amplifies the energy and cognitive benefits of HRT.

from $215/month
Learn about NAD+ →
Coming Soon

HRT + Hair Restoration

Hormonal changes are a primary driver of hair loss in women. As estrogen declines hair may thin or shed more than usual. HRT stabilizes the hormonal environment. Adding a clinician-prescribed hair restoration program addresses the follicle level directly for patients experiencing noticeable thinning alongside other symptoms.

from $141/month
Hair Restoration →

Individual programs require separate provider evaluation. Combinations at provider discretion based on health history and labs.

The Process

How It Will Work — From Assessment to First Shipment

1
Complete Your Health Assessment OnlineAnswer questions about your symptoms, health history, menstrual or menopause status, current medications, and whether you have had a hysterectomy. Takes approximately 5 minutes.
2
Async Provider ReviewA licensed independent physician reviews your intake within 24–48 hours. No sync video visit required in most states for HRT. If your provider needs additional information or orders labs they will reach out via your patient portal.
3
Labs if OrderedIf your provider orders baseline labs they will send the order to Quest or Labcorp electronically. Labs are billed directly to you — not included in HRT pricing.
4
Prescription Sent to PharmacyOnce your provider determines the appropriate formulation your prescription goes to our FDA-registered compounding pharmacy. Prepared and shipped within 2–3 business days.
∞
Quarterly ShipmentsHRT medications ship every 12 weeks with a brief async provider review before each refill to confirm continued appropriateness and address any questions.
Common Questions

HRT Questions Answered

Is HRT safe?+
Modern clinician-prescribed hormone therapy has been extensively studied. The safety profile of bioidentical estradiol — particularly transdermal formulations — differs significantly from the synthetic conjugated estrogen studied in the early 2000s research that generated concerns. Updated clinical guidance from major medical organizations now supports HRT for symptomatic women particularly when started within 10 years of menopause onset. Your provider discusses your individual risk profile with you directly.
Do I need to have gone through full menopause to start HRT?+
No. Hormone therapy can be appropriate for women in perimenopause — the transitional period before menopause — as well as during and after. Perimenopause symptoms can be significant and HRT addresses them at any stage. The key is a provider who evaluates your individual situation.
What is the difference between perimenopause and menopause?+
Perimenopause is the transitional period — typically lasting 4 to 8 years — during which hormone levels fluctuate and decline. Menopause is defined as 12 consecutive months without a menstrual period. Symptoms can be significant during both stages and HRT can be appropriate throughout.
Will HRT cause weight gain?+
HRT does not typically cause weight gain and may actually help manage the weight changes associated with hormonal decline. The weight gain many women experience during perimenopause and menopause is primarily driven by the hormonal changes themselves — not by HRT. Restoring estrogen may make weight management more responsive to diet and exercise efforts.
Can I take HRT if I have a history of breast cancer?+
This requires direct discussion with your provider. Hormone-sensitive cancers are generally considered a contraindication to estrogen therapy. However the situation varies by cancer type, treatment history, time elapsed, and individual risk factors. Non-hormonal options are available for women who cannot take estrogen. Accurate disclosure in your intake is essential.
Do I need a hysterectomy to take HRT?+
No. Women with and without a hysterectomy are candidates for HRT. Women with an intact uterus receive both estrogen and progesterone. Women who have had a hysterectomy typically receive estrogen alone. Your provider determines the appropriate protocol.
How long will I need HRT?+
This varies significantly by individual. Many women use HRT for 3 to 5 years to manage the acute transition. Others continue longer for quality of life, bone density support, and cardiovascular health. This is a decision you make with your provider over time — not a permanent commitment you make when you start.
Can I cancel after joining the waitlist?+
Yes. Joining the waitlist creates no obligation. You will be notified when enrollment opens and can choose whether to proceed at that time.
Coming Soon

Be First in Line
When We Launch

Join the waitlist now. We will notify you the moment HRT enrollment opens and give waitlist members priority access.

Questions? Email Justin@boldyouwellness.com
Licensed Physicians
Multiple Formulations
All 50 States
Cancel Anytime
Compounded medications are not FDA-approved finished drug products. Results may vary. Not all patients will qualify for treatment. Prescribing decisions are made solely by licensed independent clinicians based on individual medical evaluation. This is not medical advice.