Estradiol Pill + Progesterone
A daily oral estradiol tablet. Progesterone is added if you still have a uterus.
Best for: Women who want a simple daily pill and have no liver or clotting concerns.
Provider-prescribed estradiol and progesterone, as a pill, patch, cream or vaginal option, plus non-hormonal choices. Personalized to your symptoms and history by a licensed provider.
$79/mo, billed $237 every 12 weeks. Available in all 50 states.
Rate each one from 0 (none) to 3 (severe).
We'll show you which kind of treatment usually fits. Your provider makes the final call.
You are not imagining it
These are real, measurable effects of falling estrogen and progesterone, and they're treatable.
The science, made simple
Here's what changes, in plain words.
Estrogen helps control body temperature, sleep, mood, bone strength, and vaginal and bladder health. When it falls, those systems feel it.
Progesterone protects the uterine lining when you take estrogen, and supports sleep. If you've had a hysterectomy, you may not need it.
Hormone therapy uses estradiol, the same form of estrogen your ovaries make, at the lowest dose that eases your symptoms.
Fears about HRT come largely from a 2002 study of older hormone types in women who were, on average, past 60. Today's guidance supports HRT for many healthy women with symptoms, especially when started before 60 or within 10 years of menopause. Your provider weighs your personal risks.
Your body adjusts. Some women notice better sleep first.
Many women notice fewer hot flashes and steadier mood.
Dryness and comfort improve. Energy and libido often return.
Your provider reviews how you feel and adjusts if needed.
Typical timing. Everyone responds differently.
Formulation options
Your provider recommends a form based on your symptoms, health history and preference. One price covers every option: $79/mo, billed $237 every 12 weeks.
A daily oral estradiol tablet. Progesterone is added if you still have a uterus.
Best for: Women who want a simple daily pill and have no liver or clotting concerns.
Estradiol through the skin, by patch or daily cream. Progesterone is added if you have a uterus.
Best for: Women with certain liver or heart risk factors, or who prefer skin over a pill. Through-the-skin estrogen has a lower clot risk than pills.
Low-dose estrogen placed in the vagina, with very little reaching the rest of the body.
Best for: Women whose main symptoms are vaginal or urinary.
Low-dose paroxetine or desvenlafaxine, which can reduce hot flashes without hormones.
Best for: Women who can't take hormones, such as after a hormone-sensitive cancer or a blood clot, or who prefer not to.
Illustrations. Vaginal estrogen mainly treats local symptoms. Non-hormonal options mainly treat hot flashes.
Full transparency
Labs aren't always needed. Your provider orders them based on your symptoms and history.
Is it right for me?
HRT is a well-studied option for many women. It isn't right for everyone.
If any of these apply, non-hormonal or vaginal-only options may still be possible. Your provider talks it through.
Pricing
One monthly price for your medication and provider care.
Lab fees, if ordered, are billed by the lab. Care coaching isn't included with HRT. FSA and HSA accepted.
Works well with
Separate programs your provider may pair with HRT.
Hormone changes shift where your body stores fat. Microdosing supports the metabolic side.
Learn about microdosingFor energy and focus that hormones alone don't fully restore.
Learn about NAD+Thinning often starts in perimenopause.
Hair restorationHow it works
About 5 minutes on your symptoms, cycle and health history.
A provider licensed in your state reviews it, usually within 24 to 48 hours, and orders labs if needed.
Your prescription ships discreetly from a U.S.-licensed pharmacy.
Your provider checks in and adjusts your dose or form as you go.
Straight answers. If your question isn't here, our care team will answer it.
Don't see your city? We serve all 50 states. See all HRT locations we serve
Take the quiz. A licensed provider reviews your symptoms and history within 24 to 48 hours.